The primary philanthropy of Phi Theta Chi is breast cancer awareness. Each and every fundraiser Phi Theta Chi holds supports breast cancer and its awareness. Phi Theta Chi also adopted and now supports Women's Welfare, March of Dimes, and Feed My Starving Children.

Besides supporting their philanthropy, Phi Theta Chi Sorority openly supports any good cause and opportunity to participate in helping in any area. Examples of past and current experiences include canned food drives, alcohol awareness, and specific events such as Relay for Life and Highway Clean Up.